Giant T–U Waves Precede Torsades de Pointes in Long QT Syndrome
نویسندگان
چکیده
منابع مشابه
Giant T-U waves precede torsades de pointes in long QT syndrome: a systematic electrocardiographic analysis in patients with acquired and congenital QT prolongation.
OBJECTIVES This study sought to identify electrocardiographic (ECG) criteria that are associated with initiation of torsades de pointes (TdP) in patients with acquired (a-) and congenital (c-) long QT syndrome (LQTS). BACKGROUND Electrocardiographic criteria used as risk predictors for TdP commonly rely on a prolonged QT interval but rarely consider abnormal T-U waves. METHODS We analyzed E...
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A case is reported of electrocardiographic QT prolongation that was presumbty familial in origin. Torsades de points developed in association with the use ofdothinepin, despite the pmscription of a low dose of this drug.
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Corresponding author: Yong Seon Choi, M.D., Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, 50, Yonsei-ro, Seodaemun-gu, Seoul 120-752, Korea. Tel: 82-2-2227-4576, Fax: 82-2-364-2951, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial L...
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RESULTS No recurrence of TdP occurred within 2 h after initiation of treatment with mexiletine in all 12 patients. Macro T-wave alternans accompanied by QT prolongation, an electrocardiographic precursor of TdP that was seen in 3 patients, was also abolished by mexiletine. Treatment with mexiletine shortened the QTc interval from 599 27 ms to 514 16 ms (p 1⁄4 0.001). The interval from the peak ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2009
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2009.03.043